Physiological changes caused by COVID-19 and its consequences in the worsening of the disease: Pharmacy graduates applying Clinical Biochemistry learning

Abstract

COVID-19 is a highly lethal infection limited recently in human history. Its clinical manifestations are variable, but can be analyzed by laboratory tests that are already widely used. Pharmacists are important players in guiding patients on the care that should be taken during the course of the pandemic. The objective was to promote the discussion among Pharmacy graduates from a college in Reconcavo Baiano about the main physiological changes that occurred due to COVID-19 and its consequences on the clinical evolution of those infected. This is a meta-analysis, the methodology consisted of searching for works published in databases (PubMed, Scielo and Google Scholar). 33 articles were released from which information was extracted on 5 parameters: release of inflammatory mediators; change without carbohydrate metabolism and changes in cardiac, renal and pancreatic activities considered as predictors of worsening in cases of COVID-19. The work has limitations on the time for its execution and due to flaws in the connection during interactions on the line with students. The perspective is that the participants of this study contribute with clarification about the possible health problems caused by COVID-19 to users of the institutions in which they work as interns.